The following table identifies the distinct roles and responsibilities of professional associations, such as the American Speech-Language-Hearing Association (ASHA), and unions, such as the American Federation of Teachers (AFT) and the Service Employees International Union (SEIU).
| 
 | Professional Association | Union | 
| Role | Empowering and supporting a particular profession, discipline, or trade, the interests of individuals engaged in that domain, and the public interest. | Promoting and protecting employees who have joined together at particular worksites and/or employers to bargain for better wages and benefits, as well as improved working and safety conditions. Once a union is certified, it has the sole authority to negotiate the terms and conditions of employment for the people it represents. | 
| Principal Activities May Include: | 
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| Scope | State, National, International | Local, State, National, International (affiliated or independent) | 
| Participation | Voluntary with specific qualifications and conditions | 
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| IRS Tax Status | Predominately Non-profit 501(c)(6) | Non-profit 501(c)(5) |